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What Is Treatment-Resistant Depression?

Depression is one of the most common mental health conditions. Characterized by persistent feelings of sadness, hopelessness, and loss of interest in daily activities, depression can significantly impact an individual’s quality of life. While there are various treatment options available for depression, some individuals may not respond to traditional forms of therapy or medication. This is known as treatment-resistant depression (TRD). This can feel frustrating and overwhelming for those affected by it, but fortunately, there are still options available.

Columbia Associates offers treatment-resistant depression treatment in our locations throughout Maryland and Virginia. If you or a loved one is struggling with TRD, call 703.682.8208 today to learn more.

What Is Treatment-Resistant Depression?

Treatment-resistant depression is a form of major depressive disorder that does not respond to traditional forms of therapy and medication. It is estimated that about one-third of individuals with depression do not experience relief from their symptoms after trying multiple antidepressant medications. This can be a very challenging situation for both clients and mental health professionals, as finding the right treatment plan becomes a complex and often lengthy process.

Why do some people experience TRD? There are various factors that can contribute to the development of treatment-resistant depression. Genetics and co-occurring mental health conditions can play a role in making an individual less responsive to traditional forms of treatment. Additionally, certain medications may not be effective for everyone and can result in side effects that make it difficult to continue taking them.

Signs of Treatment-Resistant Depression

While the signs of treatment-resistant depression may vary from person to person, there are some common symptoms that can indicate that your depression is not responding adequately to treatment. They may include:

  • Persistent feelings of sadness, hopelessness, or emptiness despite taking antidepressant medication
  • Difficulty concentrating, remembering details, or making decisions
  • Fatigue or decreased energy
  • Restlessness or irritability
  • Sleep disturbances, such as insomnia or sleeping too much
  • Changes in appetite or weight
  • Persistent physical symptoms that are not relieved by treatment, such as headaches, digestive disorders, and chronic pain
  • Thoughts of death and suicide

If you notice these signs, it’s important to reach out to a healthcare professional for a comprehensive evaluation and to discuss alternative treatment options.

What Works for Treatment-Resistant Depression?

One of the most promising treatments for TRD is Spravato®. This is a nasal spray that contains esketamine, an FDA-approved medication for the treatment of depression. Studies have shown that Spravato® can significantly improve symptoms of depression in individuals who have not responded to other forms of treatment. At Columbia Associates, we offer this innovative therapy as part of our comprehensive treatment approach for TRD.

In addition to Spravato®, another option for TRD is transcranial magnetic stimulation (TMS) therapy. This non-invasive treatment involves using magnetic fields to stimulate areas of the brain that regulate mood. TMS has been FDA-approved for the treatment of depression and has shown promising results in individuals with TRD. While TMS therapy may not work for everyone, it can be an effective alternative for those who have not found relief with medication or talk therapy.

Call Columbia Associates Today for Help with TRD

At Columbia Associates, we understand the challenges of living with treatment-resistant depression and how it can impact every aspect of your life. Our team of experienced mental health professionals is dedicated to providing personalized and effective treatment for TRD. We offer a range of therapies, including TMS therapy and Spravato®, to help our clients find relief from their symptoms.

Call 703.682.8208 today to get in touch with Columbia Associates. If you’re ready to take the next step in your mental health journey, click here to reach out to our team of empathetic, mental health care experts! For existing clients, please click here and find your office location to contact your office directly.